Effects of AC-1370, a new semisynthetic cephalosporin, on phagocyte functions
نویسندگان
چکیده
منابع مشابه
Pharmacokinetic study of a new semisynthetic cephalosporin (AL-226) in rabbits.
The pharmacokinetics of AL-226, a new semi-synthetic cephalosporin, were studied after i.v. and i.m. administrations to rabbits at doses of 10, 20, 30 and 40 mg/kg. The average values of the pharmacokinetic parameters after bolus i.v. administration of the antibiotic expressed by an open two-compartment kinetic model were: alpha = 0.131 min.-1, beta = 0.0341 min-1, K12 = 0.0287 min.-1, K21 = 0....
متن کاملIn vitro antibacterial activity of cefoperazone (T-1551), a new semisynthetic cephalosporin.
Cefoperazone, a new semisynthetic cephalosporin, has a broad spectrum of antibacterial activity. It is as active as cefazolin and cefamandole against gram-positive bacteria and is more active than cefazolin and cefamandole against such gram-negative bacilli as Escherichia coli, Klebsiella pneumoniae, Proteus species, Pseudomonas aeruginosa, Citrobacter freundii, Enterobacter cloacae, and Serrat...
متن کاملIn vitro antibacterial activity of E-0702, a new semisynthetic cephalosporin.
E-0702 is an antipseudomonal cephalosporin derivative which has a broad spectrum of antibacterial activity against clinical isolates of gram-positive and gram-negative bacteria. Its in vitro antibacterial activities were less than those of cefoperazone and cefotaxime against Staphylococcus aureus and Staphylococcus epidermidis, but were significantly high against gram-negative bacteria includin...
متن کاملIn vitro and clinical studies of cefatrizine, a new semisynthetic cephalosporin.
Cefatrizine, a new oral semisynthetic cephalosporin, was evaluated in vitro and in the treatment of 18 patients with acute urinary tract infection, pneumonia, and soft tissue infection. In vitro, it was more active than cephalexin for gram-positive and gram-negative bacteria. It was also more active than cephalothin, cefazolin, and cephapirin against most of the gram-negative bacteria but less ...
متن کاملAntibacterial and pharmacokinetic properties of M14659, a new injectable semisynthetic cephalosporin.
In vitro and in vivo antibacterial activities and pharmacokinetics of M14659 were investigated. In vitro activity of M14659 was superior to that of ceftazidime against Staphylococcus aureus. Against Gram-negative bacteria except Pseudomonas aeruginosa, its activity was almost equal to that of ceftazidime. M14659 was more active against P. aeruginosa including multi-drug resistant strains than c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1983
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.23.6.874